Postural orthostatic tachycardia syndrome - Search
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  1. Overview - Postural tachycardia syndrome (PoTS)

    Verified Expert
    Also known as: postural orthostatic tachycardia syndrome
    A condition where the heart rate increases on changing the posture, such as lying to sitting up or standing. This will cause dizziness or fainting.
    How common is condition?
    Common (More than 200,000 cases per year in US)
    Is condition treatable?
    Treatments can help manage condition, no known cure
    Does diagnosis require lab test or imaging?
    Rarely requires lab test or imaging
    Time taken for recovery
    Can last several years or be lifelong
    Condition Highlight
    Common for ages 15-50
    Condition Highlight
    More common in females
    Condition Highlight
    Family history may increase likelihood for some types
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    Causes

    Verified Expert

    • The exact cause is not known. The possible causes may include:
    • Hereditary - it runs in the family
    • Underlying conditions such as diabetes, amyloidosis, sarcoidosis, and cancer
    • After a viral illness, traumatic event or pregnancy
    • Associated with autoimmune disorders such as lupus, Sjogren syndrome, and celiac disease
    • Poisoning with alcohol or certain metals
    • Chronic fatigue syndrome
    • Risk factors include:
    • More common among women between 15 to 50 years of age
    • Family history
    • Anemia
    • Anaemia

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    Symptoms

    Verified Expert
    Contact your provider if experiencing new, severe, or persistent symptoms.

    Symptoms may vary from person to person and include:

    • Rapid heartbeat
    • Light-headedness
    • Fainting
    • Fatigue
    • High/low blood pressure
    • Inability to exercise
    • Nausea
    • Anxiety
    • Blurred vision
    • Headaches

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    What causes postural orthostatic tachycardia syndrome?
    Postural orthostatic tachycardia syndrome is caused by genetic mutations, also known as pathogenic variants. Genetic mutations can be hereditary, when parents pass them down to their children, or they may occur randomly when cells are dividing.
    rarediseases.info.nih.gov

    Treatment

    Verified Expert

    Treatment mainly includes self care practices to help deal with the symptoms. Less often, medication may be used.

    Medication

    Corticosteroids: Help the body to retain sodium.

    Fludrocortisone

    Beta blockers: To decrease the heart rate.

    Atenolol

    Vasopressors: Narrow the blood vessels and act as anti-hypotensives.

    Midodrine

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    Diagnosis

    Verified Expert
    One or more of these tests may be recommended by your medical provider.
    Tilt table test is the best way to diagnose the condition. Imaging tests of the brain and blood tests may be performed to rule out other causes.

    Common tests & procedures

    Tilt table test: Blood pressure and heart rate are measured while lying on a bed and when you change into an upright position.

    Active stand test: Heart rate and blood pressure are measured after lying down, immediately upon standing and after 2, 5, 10 minutes.

    Quantitative sudomotor axon reflex test (QSART): A test that measures the autonomic nerves (involuntary) that control sweating.

    Electrocardiogram (ECG or EKG): Records the electrical activity of the heart.

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    Source: Focus Medica. For informational purposes only. Consult a medical professional for advice.
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